Mulin Liu

First Affiliated Hospital of Bengbu Medical College, China

Title: m6A methyltransferase METTL3 promotes malignant proliferation of colorectal cancer cell via the CDK4/P53/MYC signaling axis

Biography

Mulin Liu received the M.D. and Ph.D. degrees from Xi’an Jiao tong University in China. He is currently the Director of the Department of Gastroenterology, The First Affiliated Hospital, Bengbu Medical College. He is also the Director of the General Surgery Department, Bengbu Medical College. His main research interests include molecular etiology and prognosis of the etiology, pathogenesis, occurrence, and development of digestive system tumors. He is a recipient of the second and third prizes of scientific and technological progress in Anhui province.

Abstract

We used bioinformatics approaches to analyze the differences and possible biological functions of m6A-related genes in colorectal cancer (CRC). Moreover, we evaluated the key genes involved in the m6A RNA methylation process and assessed their biological functions as well as potential molecular mechanisms in malignant proliferation of CRC cells.