Single-cell and Spatial Multiomics in Cancer Research

Emerging single-cell multi-omics sequencing technologies allow the capture of multiple modalities from a cell, including its epigenome, transcriptome, epi-transcriptome and proteome. This integration combination of multiple layers of information also requires tailor-made computational tools for integrative analyses.

Multiomics  sequencing methods are ideally placed for Cancer biology tumor - heterogeneity, cancer progression and its interactions with the microenvironment, mechanisms of response or resistance to therapy research.