THEME: "Frontiers in Cancer Research and Oncology"
City University of Hong Kong, Hong Kong
Title: The role of histone mutations in human disease
K. M. CHAN graduated with BSc and received his PhD at the department of Biochemistry, the University of Hong Kong (HKU). He then moved to Mayo Clinic (Rochester MN, USA) for postdoctoral training and obtained the Edward C. Kendall Research Fellowship in Biochemistry before rejoining HKU as Research Assistant Professor in June 2013. In February 2015 he joined the Department of Biomedical Sciences (BMS), City University of Hong Kong as a tenure-track Assistant Professor and was promoted to Associate Professor in 2021. Dr Chan is interested in understanding the role of epigenetics in regulating gene expression under physiological and pathological conditions. His group is currently focusing on 1) identifying new cancer driving histone mutations and developing therapeutics for these diseases using different animal models [1,2,3] and 2) the role of novel protein factors and RNA binding proteins in X Chromosome inactivation [4].