Scholars International Conference on

Frontiers in Chemistry and Drug Discovery

THEME: "Frontiers in Drug Discovery, Development and Lead Optimization"

img2 25-26 Aug 2021
img2 ONLINE EVENT
Bayram Gunduz

Bayram Gunduz

Malatya Turgut Ozal University, Turkey

Title: Spectroscopic and Photonic Properties of Dexamethasone used in the Treatment of COVID-19 Patients


Biography

Bayram Gündüz received his bachelor’s degree in Physics from Firat University, Elazig, Turkey, 2001–2005, master degree from Solid State Physics, Firat University, 2005–2007, PhD degree from Solid State Physics, Firat University, 2007–2011. He was research assistant in Solid State Physics, Mus Alparslan University, Turkey, 2009–2011 and was Assist. Prof. Dr. in Department of Science Education, Mus Alparslan University, 2011–2017. He was an Assoc. Prof. Dr. in the same department and university, 2017-2019. He is currently an Assoc. Prof. Dr. in Malatya Turgut Özal University, since November 2019. His main achievements include organic semiconductors and optoelectronic materials: (i) electrical, optical, photonic and optoelectronic properties; (ii) fabrication of electronic and optoelectronic devices and and investigation their photophysical properties and applications such as Schottky diode, P–N heterojunction diode, metal–insulator–semiconductor junctions, solar cells, thin-film transistor, photodiode. (B) He has many articles (more than 70) published in SCI, SCI-Exp journals, which have high impact factors and has about 820 citations to his studies.

Abstract

Dexamethasone is a synthetic adrenal corticosteroid with potent anti-inflammatory properties. Dexamethasone (MK-125) is a position 9 fluorinated corticosteroid used to treat endocrine, rheumatic, collagen, dermatological, allergic, ophthalmic, gastrointestinal, respiratory, hematological, neoplastic, edematous, and other conditions. On June 16, 2020, a press release for the Randomized Evaluation of COVID-19 Treatment (RECOVERY) trial recommended the use of dexamethasone in COVID-19 patients with severe respiratory symptoms. Dexamethasone reduced deaths by approximately one-third in ventilated patients and one-fifth in patients requiring oxygen [1]. Therefore, Dexamethasone is used in the Treatment of COVID-19 Patients in some countries. In this study, we investigated the spectroscopic properties and photonic properties of Dexamethasone. We have extensively studied the absorption spectra at different concentrations and their response to light. Fig. 1 shows the absorbance spectra of the Dexamethasone for various concentrations. On the other hand, we continue to work intensively on some herbal suggestions that can be considered equivalent to Dexamethasone.