Teuta Halili

University of Prishtina, Republic of Kosova

Title: Synthesis and structural properties of some new substituted chalcone derivatives starting from 4-nitrobenzaldehyde

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Biography

I am Teuta Halili, 23 years old and I come from Kosovo. I completed primary education in my hometown, high school in the municipality of Gjilan and I have studied at the University of Prishtina "Hasan Prishtina" - Faculty of Mathematical and Natural Sciences - Department of Chemistry. I have recently started working in a regional water company, so I have the opportunity to analyze water from different regions, after taking the samples the basic determinations are made to know if the water is ready for drinking or not. An independent and self-motivated chemist with proven and tested in analitycal chemistry, numerical problems and analysis. Experienced with all levels of analytical chemistry, including quantitative and qualitative chemistry. Well-versed in analytical techniques such as UV-VIS, IR spectroscopy, Nuclear Magnetic Resonance (NMR) spectroscopy, chromatograpy, potentiometry, voltammetry, conductometry, culonometry. When I have free time I like reading novels, walking in nature, watching movies, I also have a passion for traveling.

Abstract

Chalcones are a group of plant-derived polyphenolic compounds belonging to the flavonoids family. The aims of this study were the synthesis and structural characterization of some new substituted chalcone derivatives starting from 4-nitrobenzaldehyde.

The Claisen-Schmidt condensation was used for the synthesis of chalcone derivatives but the conventional Claisen-Schmidt condensation procedure for the synthesis of substituted chalcones was occasionally modified.

The obtained syntheses were analyzed by measuring the melting points, recrystallizing them, performing chromatography and recording the IR spectra. Melting point values ranged from 101.6 ºC to 244.6 ºC, while the retention factor values ranged from 0.37 to 0.93. By interpreting the IR spectra we have confirmed the presence of functional groups, for example the groups -NO2, -OH, -OCH3, C-Cl and C-Br.

The results obtained from this study showed that the obtained chalcones are the required chalcones.