S. Belbekhouche

Université Paris Est Creteil, France

Title: Development of Tailor Made Drug Delivery System based on Polyelectrolyte Multilayer Capsules

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Biography

Sabrina Belbekhouche is an associate professor working at the East Paris Institute of Chemistry and Materials (East Paris University, France). Her core expertise is in polymer science, macromolecular assembly and surface modification. This includes the polymer modification, the study of the physical chemistry of surfaces/interfaces; and the use of controlled assembly at the sub-micrometer scale (nanoparticle, nanocapsule...) as well as stimuli-responsive systems. Current applications of her research are mainly for biological application.

Research Interest

Recent progress in supramolecular chemistry leads to unparalleled control over the composition and shape factor of colloidal systems. Among them, the design of capsules is a new expanding area of physical-chemical research.1,2 Here, we report on the development of tailor made polymer capsules for potential applications in biomedical field. The primary focus is to enhance the loading/release of therapeutic agents. The implemented strategy is mainly based on colloidal templating and self?assembly.3 Size, dispersity and concentration of the nanocapsules are easily fixed by the initial nanoparticle template, while wall thickness is dependent on the number of layers. The present strategy is advantageous in comparison with other synthetic routes because at all steps, only water is used as a solvent and not organic one. The possibility to control the mechanical property of the capsules brings new promising property which will be evidenced during the talk. The benefits of using these capsules will be presented in numerous biological applications.