THEME: "New Science & Novel technologies in the Nano Regime"
Institute of Biophysics and Biomedical Engineering Bulgarian Academy of Sciences
Title: Newly synthesized second-generation dendrimers on human fibroblasts and the mechanism of their cellular uptake
Time:
Anelia Kostadinova currently holds the position of
Associate Professor in the "Lipid-Protein Interactions" Section at
the Institute of Biophysics and Biomedical Engineering at the Bulgarian Academy
of Sciences (BAS). Her scientific interests into establishing the interaction of different types of cell lines with
synthetic or natural material, as well as nanoscale materials (nanoparticles)
for application in modern biomedicine: The evaluation of the biocompatibility
and applicability of these biomaterials is carried out by considering
cytotoxicity and following changes in the adhesive phenotype of cells, cell
contacts and especially changes in the cell boundary complex, the first
structure with which materials interact. The contribution nature of the
research is fundamental – establishing the mechanisms of the changes in the
cell membrane by means of different signaling molecules and pathways that have
an impact on the cell border complex and cell physiology.