Zeliha Selamoglu

Nigde Omer Halisdemir University, Turkey

Title: The Bee Products as Antihypertensive Therapeutics: A New Trend Study

---

Biography

Zeliha Selamoglu is a Professor in Medical Biology department of Nigde Ömer Halisdemir University, Turkey. She earned her PhD in Biology from Inonu University, She has published over 160 peerreviewed journal articles with over 2250 citations and many technical reports. She is a member of Society for Experimental Biology and Medicine: Associate Membership and European association for cancer research. She has served as Editorial Board member for many Journals.

Abstract

Hypertension has been established as a significant risk factor for morbidity and mortality worldwide. Hypertension can be defined as a raised blood pressure (BP) based on altered hemodynamics of the systemic circulation. Atherosclerotic risk factors such as hypertension and aging augment the vascular generation of reactive oxygen species (ROS). Antihypertensive and antioxidative effects of various nutrition and natural products have been claimed. Honeybee products are one of these natural matters. These have some properties such as inhibitory effect against angiotensin-converting enzyme, vasodilatory activity by parasympathetic stimulation, or repressive features on release of noradrenaline from sympathetic nerves. Moreover, a diverse range of flavonoids and polyphenol metabolites from natural agents have been showed to have vasodilating and antihypertensive properties. Increasing of ROS amounts has been showed in experimental and clinical hypertension. Early investigations implied that applying the the nitric oxide synthase inhibitor, ended up as raised BP and ROS-mediated tissue injury. The present update study evaluates current findings on the antihypertensive properties of honey bee products and their therapeutic relevance to the clinic. Therefore, these studies will shed light on new researches allowing different usages of honeybee products to keep the inner balance of body constant and give direction to the developments of new extracts and preparations.