Maria Del Pino

Houston Methodist Hospital, United States

Title: Impairment In Patients With Atrial Fibrillation: A Systematic Review And Meta-Analysis

Biography

Maria Del Pino is a dedicated bilingual nursing professional with extensive experience in nursing education, research, and clinical practice. She holds a Bachelor's degree in Nursing from Universidad Autonoma de Barcelona and two Master's degrees in Emergency Health Services and Community Nursing & Public Health. Currently pursuing a PhD in Biomedical Science, she has actively contributed to research projects, including clinical trials and meta-analyses, with a focus on atrial fibrillation treatment, stroke prevention, and quality improvement.

As a certified Cardiovascular Registered Nurse and Clinical Research Professional, Maria Del Pino has developed and delivered educational sessions for healthcare professionals, emphasizing evidence-based practice and lifelong learning. Her professional interests include collaborative research, mentoring healthcare professionals, and developing innovative educational programs to enhance healthcare delivery and improve patient outcomes.

Abstract

Background: Atrial fibrillation (AF) is a common cardiac arrhythmia associated with significant cardiovascular morbidity and mortality, as well as cognitive impairment (CI). The interplay between AF and CI is complex, involving various pathophysiological changes and numerous risk factors. Among them, depression has emerged as a significant contributor to both AF and CI, further complicating the relationship between these conditions.

Objectives: This systematic review and meta-analysis aimed to investigate the influence of depression on the development of cognitive impairment in AF patients and assess the predictive value of the CHA2DS2-VASc score for CI risk.

Methods: We searched PubMed, Scopus, and Web of Science for relevant studies without language or date restrictions. Ten studies, comprising 1,605,577 participants, were included. A random-effects model was used for meta-analysis, and heterogeneity was assessed using I2 statistics. Funnel plots and Egger’s test evaluated publication bias.

Conclusions: Our findings support the association between depression and cognitive impairment in AF patients, demonstrating the importance of addressing mental health in cardiovascular care. Future research is necessary for a comprehensive understanding of this association.