THEME: "Heartbeat of Change: Inspiring Solutions for Global Cardiac Health"
Manipal Hospital kolkata
Title: Incidence Of Coronary Artery Disease Among Copd Patients With Uncontrolled Dyspnoea Despite Optimal Bronchodilator Therapy
Suvendu Chattopadhyay completed his MBBS from the
prestigious IPGMER, Kolkata in 2012, followed by a DNB in Pulmonary Medicine in
2017 and a DM in Cardiology in 2020. After serving as a Senior Resident in
Cardiology at IPGMER from 2020 to 2023, he is currently practicing as a
Consultant Interventional Cardiologist at Manipal Hospital Broadway, Charnock
Hospital, and B.M. Birla Heart Research Centre in Kolkata.
Chattopadhyay has an extensive procedural
portfolio, having performed over 5,000 coronary and peripheral angiographies,
more than 1,000 angioplasties, over 500 permanent pacemaker implantations, and
more than 50 AICD/CRT device implantations. During his residency in Pulmonary
Medicine, he also performed over 100 bronchoscopies and more than 50 medical
thoracoscopies.
He has authored several publications in
peer-reviewed medical journals and is a regular speaker at continuing medical
education (CME) events. Dr. Chattopadhyay has also participated as a speaker or
panelist at numerous national and state-level medical conferences.
He is known for his dedication to patient care
and his unwavering commitment to academic excellence and professional
development.
Introduction: Both coronary artery disease (CAD) and chronic obstructive pulmonary disease (COPD) have high rates of morbidity and mortality. Systemic inflammation, as demonstrated in several studies of COPD patients, is also associated with atherosclerotic plaque formation. Various studies had demonstrated varying incidence of CAD among COPD patients. However, it is unclear that how much contribution of CAD is responsible for the worsening of COPD symptoms.
Aim & objective: To assess the incidence of coronary artery disease in individuals with COPD who have uncontrolled dyspnoea even with the optimal bronchodilator treatment.
Materials & Methods: This study was a hospital based observational study, cross sectional in design. This study was carried out on established COPD patients with uncontrolled dyspnoea despite optimal bronchodilator therapy for > 3 months with good adherence. History of typical angina, moderate to severe pulmonary hypertension, established CAD without revascularization or left ventricular systolic dysfunction (EF<50%) cases were excluded. Finally, 120 consecutive patients fulfilling the selection criteria were includes and underwent coronary angiography.
Result: The study population was male predominant (67.5%), coronary angiography showed 78 out of 120 (65%) COPD patients who had uncontrolled dyspnoea despite optimal medical management for COPD, had critical coronary artery disease. Among various common risk factors smoking and diabetes were significantly associated with critical CAD (p value 0.00023 and 0.0045 respectively). Ischaemic pattern in ECG was present only in 48.3% cases.
Conclusion: Significant co-association of critical CAD was found in COPD patients who remained symptomatic despite adequate bronchodilator medication; therefore, coronary angiography should be done in those cases.