Mohamed Yasir

California Institute of Behavioral Neurosciences and Psychology, CA

Title: Application of Nanotechnology for Diagnosis and Drug Delivery in Atherosclerosis: A New Horizon of Treatment

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Biography

Dr. Mohamed Yasir is a young physician and researcher at VJ hospital, Tirunelveli, India. Dr. Yasir received his medical degree from Kursk State Medical University, Russian Federation and is pursuing his Internal Medicine residency in the US. Currently, as a remote researcher at California Institute of Behavioral Neurosciences and Psychology, US, Dr Yasir is co-authoring several papers and has already published two articles in high-indexed journals. Dr. Yasir plans to become a physician-scientist in the field of Critical Care Medicine.

Abstract

Cardiovascular diseases are the leading cause of death worldwide, with atherosclerosis being a prominent risk factor for their development. The current diagnostic criteria for atherosclerosis rely primarily on imaging techniques, including an angiogram. However, current diagnostic procedures fail to provide insights into the plaque's burden and composition. Therefore, nanotechnology is recommended as a novel drug delivery method in treating atherosclerosis and resulting cardiovascular diseases to enhance clinical outcomes. This review discusses the different approaches in which nanotechnology can be applied in the diagnosis and drug delivery of cardiovascular diseases.

A systematic review was carried out in line with the PRISMA reporting guidelines, with the literature databases PubMed, Scopus, and Web of Science being screened for relevant literature. Any study that discussed and reported on the application of nanotechnology for either the diagnosis or drug delivery in atherosclerotic patients was included in this review, with each novel design identified in the citations being contrasted to that of the other literature. Moreover, the efficacy of this technology was compared to current diagnostic and drug delivery methods. The search strategy yielded fourteen studies relevant to the aims of this review. Nine assessed the therapeutic applications of nanotechnology, three solely assessed the diagnostic applications of nanotechnology, and two discussed the diagnostic and therapeutic applications. The nanoparticle designs differed significantly between studies; however, all noted a superior therapeutic and diagnostic benefit compared to current approaches to diagnosing and treating atherosclerosis.

Multifunctional nanoparticles are a feasible and appropriate novel approach to diagnosing and treating atherosclerosis.