THEME: "Fostering Advancements in Nanoscience and Nanotechnology"
Hebei University of Technology, China
Title: Human Nanomedicine: Nanomaterials in the Clinic
Thomas J. Webster’s (H
index: 115; Google Scholar) degrees are in chemical engineering from the
University of Pittsburgh (B.S., 1995; USA) and in biomedical engineering from
RPI (Ph.D., 2000; USA). He has served as a professor at Purdue (2000-2005),
Brown (2005-2012), and Northeastern (2012-2021; serving as Chemical Engineering
Department Chair from 2012 - 2019) Universities and has formed over a dozen
companies who have numerous FDA approved medical products currently improving
human health. He is currently helping
those companies and serves as an adjunct professor at Hebei University of
Technology, Saveetha University, Vellore Institute of Technology, UFPI, and
others. Dr. Webster has numerous awards
including: 2020, World Top 2% Scientist by Citations (PLOS); 2020, SCOPUS
Highly Cited Research (Top 1% Materials Science and Mixed Fields); 2021,
Clarivate Top 0.1% Most Influential Researchers (Pharmacology and Toxicology);
2022, Best Materials Science
Scientist by Citations (Research.com); and is a fellow of over 8
societies. Prof. Webster has over 1,350
publications to his credit with over 53,000 citations
Nanomaterials have been
widely tested in vitro and in small order animal studies for decades. Results
have shown greater tissue growth, decreased bacteria growth, and inhibited
inflammation. However, few studies exist examining human tissue response to nanomaterials.
This presentation presents a cohort study of nano implants inserted into
humans. In particular, one study includes the implantation of nanotextured
spinal implants into over 14,000 patients over the past 5 years. Results
demonstrated no cases of infections or other implant failures which is
significantly better than statistics on conventional spinal implants which have
up to 20% failure rates. This study will further explain that nano implants
mimic the natural nano texture of bone itself and possess surface energy that
can competitively increase the adsorption of proteins known to promote
osteoblast (bone forming cells) functions, decrease bacteria functions, and
limit inflammatory cell functions. As such, this presentation will cover the
few human clinical studies on nano implants showing improved human health.