THEME: "Recent Research Methodologies and Discoveries in Physics and Quantum Physics"
Topmed medical Centre, Romania
Title: Comparison of Treatment Planning Techniques for a Synchronous Bilateral Breast Cancer Patient in the Setting of a Hypo fractionated Approach
My name is
Ghizela Ana Maria Salagean, I am a medical physicist in my 4th year
of activity, currently enrolled in my second year of PhD studies at University
of Babes Bolyai Cluj-Napoca.During my university studies and later due to my
professional activities I have developed an interest in research, that is why I
have decided to pursue a PhD focused on bolus material. Over the years, I have
become a communicative, dynamic, and sociable person. I can say that I am an ambitious person, when I set my
mind to something, I do not give up until I achieve it. My interest in radiotherapy mostly is focused on
breast cancer and bolus materials, but I like the dosimetry part also.
Synchronous bilateral breast cancer (SBBC) represents
a challenge among breast cancer patients, most cases requiring adjuvant
radiotherapy. The purpose of this study was to evaluate the optimal
radiotherapy (RT) plan technique for a case of SBBC, after breast-conserving
surgery.
Materials/Methods: We present the case of an SBBC cancer patient, who
underwent bilateral sectorectomy with sentinel node biopsy with pathology
revealing: pT2N0sn (right side), pT1N0sn (left side). Adjuvant treatment
consisted of chemotherapy and bilateral adjuvant radiotherapy to a dose of
40.05Gy in 15 fractions. Four different bilateral breast cancer treatment
techniques were evaluated, using a single isocentre for the dynamic multi-leaf
collimator intensity-modulated radiation therapy (dMLC-IMRT), tangential
volumetric modulated arc therapy (t-VMAT) and volumetric modulated arc therapy
(VMAT) plans, and a double isocentre technique for three-dimensional conformal
radiation therapy (3D-CRT) plan, respectively.
Conclusion: SBBC irradiation using a hypo fractionated schedule
with single isocentre dMLC-IMRT plan is technically feasible, practical, and
safe regarding OARs. We identified the IMRT approach as the optimal one in our
arsenal. We wish to further analyze e.g.gated techniquesandtreatmentdeliverytimes.