Weixi Shen

Shenzhen Tianyou Medical Institute, China

Title: Safeguarding Humanity from Severe Harm of Infectious Disease Outbreaks by Decipher Scientific Enigmas of Cytokine Storm

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Biography

Weixi Shen graduated from Peking University as MS in 1989 and from Peking Union Medical College, Chinese Academy of Medical Sciences with MD in 1999. He is president of Shenzhen Anti-cancer Association, Shenzhen Chairman of Tumor Prevention and Treatment Union, Council Member of Tumor Committee of World Chinese Medicine Union. Over 100 papers have been published in national and international journals. His specialization focuses on comparative research on TCM and western medicine and medical oncology. He is director of Hongkong Tianyou Medical Research Institute and Shenzhen Tianyou Medical Institute, professor of Shenzhen People’s Hospital, Southern University of Science and Technology. He presided over the National Basic Research Program of China (973 Program) projects under the Ministry of Science and Technology, National Natural Science Foundation of China projects, and major projects in Shenzhen.  

Abstract

The infectious disease outbreaks posed substantial threats to public and society. Consequently, establishing scientific prevention/treatment measures to combat such outbreaks is of paramount importance. The key harm of infection outbreaks stems in their high mortality rate. As there are no specific drugs for viruses, it is mainly viral outbreaks that may pose serious harm to humanity. Medical research has demonstrated that the death caused by viral infections is cytokine storm (CS). If medicine can solve CS, develop precision diagnostics/therapeutic strategies, significantly reduce the mortality, infectious outbreaks will not cause substantial harm. After 30 years of comparative research on Chinese and Western medicine, the author has established a new medical theory for precisely diagnosing/treating CS. Its core pattern are as follows: The meaning of CS is an overall dysfunctional status of cytokine network, which is characterized by dual abnormalities in the cytokine expression pattern and intensity. For example, cytokine pattern of COVID-19 is marked by abnormally elevated activity of TGF-?. The number of cytokine patterns for human diseases is limited, totaling around 10+ types. The characteristics of cytokine patterns can be identified based on manifestations of diseases. The author has established a new medical theory for identifying cytokine patterns through manifestations. Contemporary medical practices using hormones and antibodies to treat CS represent blind therapy and are not optimal approaches, whereas integrated Chinese and Western medicine offers the best comprehensive treatment method. The closed-loop theoretical framework of "characteristic assessment—precise classification—targeted intervention," constructed based on manifestations, has resolved the long-standing key scientific challenges of CS perplexed medicine for the five decades. Regardless of the outbreaks that may emerge globally in the future, the theory can promptly identify CS based on manifestations, providing authoritative guidance to the medical community, governments, the WHO in formulating scientific response strategies, precision treatment protocols.