THEME: "Novel Advancements in Cancer Science and Therapy"
City University of Hong Kong, Hong Kong, CHINA
Title: The role of histone mutations in human disease
Dr K. M. CHAN graduated
with BSc and received his PhD at the department of Biochemistry, the University
of Hong Kong (HKU). He then moved to Mayo Clinic (Rochester MN, USA) for
postdoctoral training and obtained the Edward C. Kendall Research Fellowship in
Biochemistry. In February 2015 he joined the Department of Biomedical Sciences
(BMS), City University of Hong Kong as a tenure-track Assistant Professor and
was promoted to Associate Professor in 2021. Dr Chan is interested in understanding the role of epigenetics
in regulating gene expression under physiological and pathological conditions.
His group is currently focusing on 1) identifying new cancer driving histone
mutations and developing therapeutics for these diseases using different animal
models [1,2,3] and 2) the role of novel protein factors and RNA binding
proteins in X Chromosome inactivation.