Takaki Shimura

Sosei Ltd. Biomedical Research Lab, Japan

Title: Neuropsychological test CKPT to evaluate the effects of therapy and lifestyle changes for dementia prevention

---

Biography

Takaki Shimura is a distinguished expert in biomedical engineering and healthcare innovation, particularly in the field of dementia care. Since 2009, he has served as the founder of the Biomedical Research Lab. and established daycare service facilities under Sosei Ltd. to apply his inventions in real-world settings for the benefit of elderly individuals with dementia.

From 2000 onward, Professor Shimura held a faculty position at Tokai University, where he focused his research on biomedical engineering solutions for dementia. Prior to his academic career, he spent 35 years in the research and development sector at Fujitsu Ltd. and Fujitsu Laboratories Ltd. (1965–2000). His contributions during this period include the development of advanced medical imaging technologies such as ultrasound and X-ray imaging using flat panel detectors, as well as innovations in remote healthcare systems.

Abstract

Background: Research on treatment techniques for dementia is shifting from Dementia to MCI (Mild Cognitive Impairment). Specifically, drugs such as Lecanemab and Donanemab have emerged to slow the progression of Alzheimer's disease. Additionally, recent international conferences have presented research reports on preventive therapies for dementia prior to MCI.

Objectives: Overview various therapies in the preclinical stage before MCI and WHO’s Risk Factors for Dementia. Furthermore, discuss the advantages of CKPT in evaluating the effectiveness of those therapies.

Methods: Using samples from the CKPT, I will introduce what kind of test it is. Next, I will use the prototype English version of CKPT to deepen understanding.

Results: To demonstrate the effectiveness of CKPT, I applied CKPT to individuals aged 60 and over in the preclinical stage, showing the reality that as the age of those who claim 'I am healthy' progresses, their claims increasingly diverge from the actual state.

Conclusion: An overview of the research on therapies aimed at preventing dementia targeting stages prior to MCI was provided. Furthermore, it demonstrated that the neuropsychological test CKPT is effective as a method for evaluating the effects of these therapies.