THEME: "Future Directions: Pioneering Mental Health and Well-being Initiatives"
23-24 Nov 2026
Holiday Inn Express Bangkok, Thailand
Institute of Mental Health, Singapore
Too Bright to Fail, Too Complex to Fit: Twice-Exceptionality in an Adolescent with ADHD, Autism, and Complex Mood and Behavioural Dysregulation
Dr
Alena Foong is a fourth-year psychiatry resident at the Institute of Mental Health (IMH),
Singapore. She
holds an MD from the University of New South Wales (UNSW). With a strong
clinical interest in child/adolescent psychiatry, Dr Foong has rotated through
child/adolescent units during her training as well as in her earlier years as a
medical student.
Twice-exceptional (2e) individuals possess high
cognitive ability alongside one or more neurodevelopmental or psychiatric
conditions, yet clinical and educational services typically assess giftedness
and disability within separate frameworks, obscuring both intervention
priorities and prognosis. We present a 13-year-old girl with
attention-deficit/hyperactivity disorder and autism spectrum disorder, with
cognitive testing in the extremely high range, who developed progressive mood
and behavioural dysregulation over eighteen months, including recurrent
self-harm, suicidal ideation, and escalating aggression culminating in an
emergency psychiatric admission. Sequential diagnoses of major depressive
disorder and oppositional defiant disorder were added despite trials of an
SSRI, stimulant medication, and an antipsychotic, with limited sustained
improvement. Multidisciplinary review suggested her presentation reflected the
interaction, rather than the simple sum, of her exceptionalities: high
intelligence masking early distress, autism-related rigidity intensifying
oppositional behaviour, and a coercive parent-child cycle reinforcing
dysregulation. Applying an operational definition of twice-exceptionality
reframed the case as a comorbidity effect requiring integrated, rather than
sequential, management. Drawing on evidence from a strengths-based,
talent-focused school programme that produced sustained cognitive, emotional,
and social growth in 2e students, we argue that psychiatric management of
twice-exceptional youth should incorporate strengths-based strategies alongside
standard pharmacological and psychotherapeutic approaches, rather than
defaulting to purely deficit-oriented treatment. This case highlights the need
for assessment and management models that account for the interactive effects
of giftedness and disability in this under-recognised population.